@Ellen_Sligh1 Hi Ellen, since AppSheet locates columns based on indices (column 1, column 2, column 3, etc.), theoretically speaking this should work. However, it is definitely not recommended, as it might lead to subtle bugs, especially if you need to change the column structure of your table and regenerate its schema.
Apart from the technical issues, another reason why we discourage this is because the column headers are meant to inform the app users of the type of information they are providing/viewing. For instance, suppose the column header is originally “I agree”, and upon seeing this in a form view, the app user selects “Yes”. However, later on the column header in the underlying spreadsheet might change to “I disagree”, even though the data provided by the user remains “Yes”. Obviously this can lead to serious misunderstanding and even misuse of the information provided by the app user.