Here is a possible option:
Add a column to your spreadsheet called “Status”.
Regenerate your table
Make this row hidden (uncheck the “Show” option)
Make the initial value = “Editable”
Make sure the column does not reset on edit
Go in each row, and make the Editable expression = [Status]=“Editable”
Create an action that changes data in this row
Select the column “Status”, and put in the value “Not editable”
Go to UX < Views, and search for the _Form view of your table
Go to “Behavior” in this view
Add the action to be triggered when the form is saved
Now, it will be editable only the first time.
Another possibly easier option:
Go to behavior > Actions
Find the system Edit button for that table view
Show it only if your first column ISBLANK: ISBLANK[Column 1]. That way, when you save, the column will not be blank, the expression will return false, and the edit button will not show when the first column has been filled out.
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